Background and aim: Prognostic stratification of acute pulmonary embolism (PE) represents the cornerstone of modern management of this potentially life-threatening disease. In the latest years, a lot of clinical prognostic models have been validated. However, these are yet underused in clinical practice, especially in real world populations. The aim of our study was to test the prognostic ability of the Simplified Pulmonary Embolism Severity Index (sPESI) score in a real world population. Methods: Data records of 452 patients that were discharged for acute PE from 28 Internal Medicine wards of Tuscany (Italy) were retrospectively analysed. sPESI was calculated in the identical manner as the original study. Prognostic ability of sPESI score for predicting in-hospital all-cause and PE-related mortality was tested by using Areas under Receiver Operating Characteristics (ROC) curve (AUC). Results: 15.2% of patients were classified as sPESI score 0, whereas 84.8% were classified as sPESI ≥ 1. All causes of in-hospital mortality were 10.95% (5.75% PE-related) in patients with sPESI score ≥ 1 and 0% (0% PE-related) in sPESI score 0. AUC for all causes of mortality was 0.694 (95% CI: 0.650-0.736), whereas it was 0.702 (95% CI: 0.657-0.743) for PE-related mortality. Conclusion: In a real world population, sPESI is a good prognosticator for all causes of in-hospital and PE-related mortality and its use should be encouraged.
| Published in | International Journal of Clinical and Experimental Medical Sciences (Volume 1, Issue 2) |
| DOI | 10.11648/j.ijcems.20150102.14 |
| Page(s) | 22-26 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Pulmonary Embolism, Prognosis, PESI Score
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APA Style
Luca Masotti, Grazia Panigada, Giancarlo Landini, Filippo Pieralli, Francesco Corradi, et al. (2015). Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report. International Journal of Clinical and Experimental Medical Sciences, 1(2), 22-26. https://doi.org/10.11648/j.ijcems.20150102.14
ACS Style
Luca Masotti; Grazia Panigada; Giancarlo Landini; Filippo Pieralli; Francesco Corradi, et al. Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report. Int. J. Clin. Exp. Med. Sci. 2015, 1(2), 22-26. doi: 10.11648/j.ijcems.20150102.14
AMA Style
Luca Masotti, Grazia Panigada, Giancarlo Landini, Filippo Pieralli, Francesco Corradi, et al. Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report. Int J Clin Exp Med Sci. 2015;1(2):22-26. doi: 10.11648/j.ijcems.20150102.14
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author = {Luca Masotti and Grazia Panigada and Giancarlo Landini and Filippo Pieralli and Francesco Corradi and Salvatore Lenti and Rino Migliacci and Carlo Nozzoli and Maddalena Grazzini and Lucia Ciucciarelli and Alessandro Morettini and Sara Bucherelli and Alessandra Petrioli and Carlotta Casati and Mario Felici and Luciano Ralli and Stefano Arrigucci and Laila Teghini and Giovanni Antonio Porciello and Stefano Spolveri and Daniele Baldoni and Anna Frullini and Barbara Cimolato and Gianni Lorenzini and Alessandro Pampana and Guidantonio Rinaldi and Maria Chiara Bertieri and Raffaele Laureano and Stefano Tatini and Alberto Fortini and Chiara Angotti and Valerio Verdiani and Anna Maria Romagnoli and Irene Cascinelli and Alberto Camaiti and Nicola Mumoli and Marco Cei and Stefano Giuntoli and Massimo Alessandri and Alessandro De Palma and Maurizio Manini and Veronica De Crescenzo and Michele Piacentini and Carlo Passaglia and Giancarlo Tintori and Carlo Palermo and Alba Dainelli and Roberto Andreini and Giuseppa Levantino and Plinio Fabiani and Lucia Raimondi and Massimo Di Natale and Filippo Risaliti and Rossella Nassi and Roberta Mastriforti and Roberto Cappelli and Michele Voglino and Paola Lambelet and Stefano Fascietti and Adriano Cioppi and Valentina Carli and Alessandro Tafi and Simone Meini and Emilio Santoro and Claudia Rosi},
title = {Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report},
journal = {International Journal of Clinical and Experimental Medical Sciences},
volume = {1},
number = {2},
pages = {22-26},
doi = {10.11648/j.ijcems.20150102.14},
url = {https://doi.org/10.11648/j.ijcems.20150102.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20150102.14},
abstract = {Background and aim: Prognostic stratification of acute pulmonary embolism (PE) represents the cornerstone of modern management of this potentially life-threatening disease. In the latest years, a lot of clinical prognostic models have been validated. However, these are yet underused in clinical practice, especially in real world populations. The aim of our study was to test the prognostic ability of the Simplified Pulmonary Embolism Severity Index (sPESI) score in a real world population. Methods: Data records of 452 patients that were discharged for acute PE from 28 Internal Medicine wards of Tuscany (Italy) were retrospectively analysed. sPESI was calculated in the identical manner as the original study. Prognostic ability of sPESI score for predicting in-hospital all-cause and PE-related mortality was tested by using Areas under Receiver Operating Characteristics (ROC) curve (AUC). Results: 15.2% of patients were classified as sPESI score 0, whereas 84.8% were classified as sPESI ≥ 1. All causes of in-hospital mortality were 10.95% (5.75% PE-related) in patients with sPESI score ≥ 1 and 0% (0% PE-related) in sPESI score 0. AUC for all causes of mortality was 0.694 (95% CI: 0.650-0.736), whereas it was 0.702 (95% CI: 0.657-0.743) for PE-related mortality. Conclusion: In a real world population, sPESI is a good prognosticator for all causes of in-hospital and PE-related mortality and its use should be encouraged.},
year = {2015}
}
TY - JOUR T1 - Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report AU - Luca Masotti AU - Grazia Panigada AU - Giancarlo Landini AU - Filippo Pieralli AU - Francesco Corradi AU - Salvatore Lenti AU - Rino Migliacci AU - Carlo Nozzoli AU - Maddalena Grazzini AU - Lucia Ciucciarelli AU - Alessandro Morettini AU - Sara Bucherelli AU - Alessandra Petrioli AU - Carlotta Casati AU - Mario Felici AU - Luciano Ralli AU - Stefano Arrigucci AU - Laila Teghini AU - Giovanni Antonio Porciello AU - Stefano Spolveri AU - Daniele Baldoni AU - Anna Frullini AU - Barbara Cimolato AU - Gianni Lorenzini AU - Alessandro Pampana AU - Guidantonio Rinaldi AU - Maria Chiara Bertieri AU - Raffaele Laureano AU - Stefano Tatini AU - Alberto Fortini AU - Chiara Angotti AU - Valerio Verdiani AU - Anna Maria Romagnoli AU - Irene Cascinelli AU - Alberto Camaiti AU - Nicola Mumoli AU - Marco Cei AU - Stefano Giuntoli AU - Massimo Alessandri AU - Alessandro De Palma AU - Maurizio Manini AU - Veronica De Crescenzo AU - Michele Piacentini AU - Carlo Passaglia AU - Giancarlo Tintori AU - Carlo Palermo AU - Alba Dainelli AU - Roberto Andreini AU - Giuseppa Levantino AU - Plinio Fabiani AU - Lucia Raimondi AU - Massimo Di Natale AU - Filippo Risaliti AU - Rossella Nassi AU - Roberta Mastriforti AU - Roberto Cappelli AU - Michele Voglino AU - Paola Lambelet AU - Stefano Fascietti AU - Adriano Cioppi AU - Valentina Carli AU - Alessandro Tafi AU - Simone Meini AU - Emilio Santoro AU - Claudia Rosi Y1 - 2015/06/25 PY - 2015 N1 - https://doi.org/10.11648/j.ijcems.20150102.14 DO - 10.11648/j.ijcems.20150102.14 T2 - International Journal of Clinical and Experimental Medical Sciences JF - International Journal of Clinical and Experimental Medical Sciences JO - International Journal of Clinical and Experimental Medical Sciences SP - 22 EP - 26 PB - Science Publishing Group SN - 2469-8032 UR - https://doi.org/10.11648/j.ijcems.20150102.14 AB - Background and aim: Prognostic stratification of acute pulmonary embolism (PE) represents the cornerstone of modern management of this potentially life-threatening disease. In the latest years, a lot of clinical prognostic models have been validated. However, these are yet underused in clinical practice, especially in real world populations. The aim of our study was to test the prognostic ability of the Simplified Pulmonary Embolism Severity Index (sPESI) score in a real world population. Methods: Data records of 452 patients that were discharged for acute PE from 28 Internal Medicine wards of Tuscany (Italy) were retrospectively analysed. sPESI was calculated in the identical manner as the original study. Prognostic ability of sPESI score for predicting in-hospital all-cause and PE-related mortality was tested by using Areas under Receiver Operating Characteristics (ROC) curve (AUC). Results: 15.2% of patients were classified as sPESI score 0, whereas 84.8% were classified as sPESI ≥ 1. All causes of in-hospital mortality were 10.95% (5.75% PE-related) in patients with sPESI score ≥ 1 and 0% (0% PE-related) in sPESI score 0. AUC for all causes of mortality was 0.694 (95% CI: 0.650-0.736), whereas it was 0.702 (95% CI: 0.657-0.743) for PE-related mortality. Conclusion: In a real world population, sPESI is a good prognosticator for all causes of in-hospital and PE-related mortality and its use should be encouraged. VL - 1 IS - 2 ER -
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