The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer

Peng Hai Yan; Shen Wei Xing; Cheng Hai Bo

doi:doi:10.11648/j.ijcm.20210504.11

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The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer

Peng Hai Yan, Shen Wei Xing, Cheng Hai Bo

Published in International Journal of Chinese Medicine (Volume 5, Issue 4)

Received: 22 November 2021 Accepted: 8 December 2021 Published: 24 December 2021

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Abstract

Background: Colorectal cancer has high incidence and mortal rate in China. Chronic inflammatory intestine diseases are ascribed to precancerous lesion of colorectal cancer because of its close relationship with each other. TCM therapy has good effect in the prevention and treatment of inflammatory bowel diseases related colorectal cancer. Objective: To explore the preventive and therapeutic effects of Coptis chinensis and traditional Chinese medicine compound containing Coptis chinensis on inflammatory bowel disease and colorectal cancer. Methods: This paper reviews the sections in classical TCM books and recent report of clinical and experimental research on the formulars composed of Coptidis Rhizoma and the single drug in treating ulcerative colitis, intestinal polyps and colorectal cancer. By analyzing the data reported in the original literature, The mostly applied herbal formulas in the clinic including Gegen Qinlian Decoction, Dark Plum Pill and Banxia Xiexin Decoction were studied in detail. Results: Coptidis Rhizoma has the function of clearing away heat and drying dampness, purging fire and detoxification, benefiting intestine and stopping diarrhea. Several formulas composed of Coptidis Rhizoma are applied to treat inflammatory bowel diseases and colorectal cancer. Conclusion: Coptidis Rhizoma and its composition has the function of inhibiting intestinal inflammation, regulating intestinal flora, protecting intestinal barrier, and etc.

Published in	International Journal of Chinese Medicine (Volume 5, Issue 4)
DOI	10.11648/j.ijcm.20210504.11
Page(s)	53-56
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Coptidis Rhizoma, Inflammatory Bowel Diseases, Colorectal Cancer, Clinical Study, Experimental Research

References

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APA Style

Peng Hai Yan, Shen Wei Xing, Cheng Hai Bo. (2021). The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer. International Journal of Chinese Medicine, 5(4), 53-56. https://doi.org/10.11648/j.ijcm.20210504.11

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ACS Style

Peng Hai Yan; Shen Wei Xing; Cheng Hai Bo. The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer. Int. J. Chin. Med. 2021, 5(4), 53-56. doi: 10.11648/j.ijcm.20210504.11

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AMA Style

Peng Hai Yan, Shen Wei Xing, Cheng Hai Bo. The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer. Int J Chin Med. 2021;5(4):53-56. doi: 10.11648/j.ijcm.20210504.11

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@article{10.11648/j.ijcm.20210504.11,
  author = {Peng Hai Yan and Shen Wei Xing and Cheng Hai Bo},
  title = {The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer},
  journal = {International Journal of Chinese Medicine},
  volume = {5},
  number = {4},
  pages = {53-56},
  doi = {10.11648/j.ijcm.20210504.11},
  url = {https://doi.org/10.11648/j.ijcm.20210504.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20210504.11},
  abstract = {Background: Colorectal cancer has high incidence and mortal rate in China. Chronic inflammatory intestine diseases are ascribed to precancerous lesion of colorectal cancer because of its close relationship with each other. TCM therapy has good effect in the prevention and treatment of inflammatory bowel diseases related colorectal cancer. Objective: To explore the preventive and therapeutic effects of Coptis chinensis and traditional Chinese medicine compound containing Coptis chinensis on inflammatory bowel disease and colorectal cancer. Methods: This paper reviews the sections in classical TCM books and recent report of clinical and experimental research on the formulars composed of Coptidis Rhizoma and the single drug in treating ulcerative colitis, intestinal polyps and colorectal cancer. By analyzing the data reported in the original literature, The mostly applied herbal formulas in the clinic including Gegen Qinlian Decoction, Dark Plum Pill and Banxia Xiexin Decoction were studied in detail. Results: Coptidis Rhizoma has the function of clearing away heat and drying dampness, purging fire and detoxification, benefiting intestine and stopping diarrhea. Several formulas composed of Coptidis Rhizoma are applied to treat inflammatory bowel diseases and colorectal cancer. Conclusion: Coptidis Rhizoma and its composition has the function of inhibiting intestinal inflammation, regulating intestinal flora, protecting intestinal barrier, and etc.},
 year = {2021}
}

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TY  - JOUR
T1  - The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer
AU  - Peng Hai Yan
AU  - Shen Wei Xing
AU  - Cheng Hai Bo
Y1  - 2021/12/24
PY  - 2021
N1  - https://doi.org/10.11648/j.ijcm.20210504.11
DO  - 10.11648/j.ijcm.20210504.11
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 53
EP  - 56
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20210504.11
AB  - Background: Colorectal cancer has high incidence and mortal rate in China. Chronic inflammatory intestine diseases are ascribed to precancerous lesion of colorectal cancer because of its close relationship with each other. TCM therapy has good effect in the prevention and treatment of inflammatory bowel diseases related colorectal cancer. Objective: To explore the preventive and therapeutic effects of Coptis chinensis and traditional Chinese medicine compound containing Coptis chinensis on inflammatory bowel disease and colorectal cancer. Methods: This paper reviews the sections in classical TCM books and recent report of clinical and experimental research on the formulars composed of Coptidis Rhizoma and the single drug in treating ulcerative colitis, intestinal polyps and colorectal cancer. By analyzing the data reported in the original literature, The mostly applied herbal formulas in the clinic including Gegen Qinlian Decoction, Dark Plum Pill and Banxia Xiexin Decoction were studied in detail. Results: Coptidis Rhizoma has the function of clearing away heat and drying dampness, purging fire and detoxification, benefiting intestine and stopping diarrhea. Several formulas composed of Coptidis Rhizoma are applied to treat inflammatory bowel diseases and colorectal cancer. Conclusion: Coptidis Rhizoma and its composition has the function of inhibiting intestinal inflammation, regulating intestinal flora, protecting intestinal barrier, and etc.
VL  - 5
IS  - 4
ER  -

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Author Information

Peng Hai Yan

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
Shen Wei Xing

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
Cheng Hai Bo

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China

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Plain Text BibTeX RIS

APA Style

Peng Hai Yan, Shen Wei Xing, Cheng Hai Bo. (2021). The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer. International Journal of Chinese Medicine, 5(4), 53-56. https://doi.org/10.11648/j.ijcm.20210504.11

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ACS Style

Peng Hai Yan; Shen Wei Xing; Cheng Hai Bo. The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer. Int. J. Chin. Med. 2021, 5(4), 53-56. doi: 10.11648/j.ijcm.20210504.11

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AMA Style

Peng Hai Yan, Shen Wei Xing, Cheng Hai Bo. The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer. Int J Chin Med. 2021;5(4):53-56. doi: 10.11648/j.ijcm.20210504.11

Copy | Download

@article{10.11648/j.ijcm.20210504.11,
  author = {Peng Hai Yan and Shen Wei Xing and Cheng Hai Bo},
  title = {The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer},
  journal = {International Journal of Chinese Medicine},
  volume = {5},
  number = {4},
  pages = {53-56},
  doi = {10.11648/j.ijcm.20210504.11},
  url = {https://doi.org/10.11648/j.ijcm.20210504.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20210504.11},
  abstract = {Background: Colorectal cancer has high incidence and mortal rate in China. Chronic inflammatory intestine diseases are ascribed to precancerous lesion of colorectal cancer because of its close relationship with each other. TCM therapy has good effect in the prevention and treatment of inflammatory bowel diseases related colorectal cancer. Objective: To explore the preventive and therapeutic effects of Coptis chinensis and traditional Chinese medicine compound containing Coptis chinensis on inflammatory bowel disease and colorectal cancer. Methods: This paper reviews the sections in classical TCM books and recent report of clinical and experimental research on the formulars composed of Coptidis Rhizoma and the single drug in treating ulcerative colitis, intestinal polyps and colorectal cancer. By analyzing the data reported in the original literature, The mostly applied herbal formulas in the clinic including Gegen Qinlian Decoction, Dark Plum Pill and Banxia Xiexin Decoction were studied in detail. Results: Coptidis Rhizoma has the function of clearing away heat and drying dampness, purging fire and detoxification, benefiting intestine and stopping diarrhea. Several formulas composed of Coptidis Rhizoma are applied to treat inflammatory bowel diseases and colorectal cancer. Conclusion: Coptidis Rhizoma and its composition has the function of inhibiting intestinal inflammation, regulating intestinal flora, protecting intestinal barrier, and etc.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - The Preventive and Therapeutic Effect of Coptidis Rhizoma on Inflammatory Bowel Diseases and Colorectal Cancer
AU  - Peng Hai Yan
AU  - Shen Wei Xing
AU  - Cheng Hai Bo
Y1  - 2021/12/24
PY  - 2021
N1  - https://doi.org/10.11648/j.ijcm.20210504.11
DO  - 10.11648/j.ijcm.20210504.11
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 53
EP  - 56
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20210504.11
AB  - Background: Colorectal cancer has high incidence and mortal rate in China. Chronic inflammatory intestine diseases are ascribed to precancerous lesion of colorectal cancer because of its close relationship with each other. TCM therapy has good effect in the prevention and treatment of inflammatory bowel diseases related colorectal cancer. Objective: To explore the preventive and therapeutic effects of Coptis chinensis and traditional Chinese medicine compound containing Coptis chinensis on inflammatory bowel disease and colorectal cancer. Methods: This paper reviews the sections in classical TCM books and recent report of clinical and experimental research on the formulars composed of Coptidis Rhizoma and the single drug in treating ulcerative colitis, intestinal polyps and colorectal cancer. By analyzing the data reported in the original literature, The mostly applied herbal formulas in the clinic including Gegen Qinlian Decoction, Dark Plum Pill and Banxia Xiexin Decoction were studied in detail. Results: Coptidis Rhizoma has the function of clearing away heat and drying dampness, purging fire and detoxification, benefiting intestine and stopping diarrhea. Several formulas composed of Coptidis Rhizoma are applied to treat inflammatory bowel diseases and colorectal cancer. Conclusion: Coptidis Rhizoma and its composition has the function of inhibiting intestinal inflammation, regulating intestinal flora, protecting intestinal barrier, and etc.
VL  - 5
IS  - 4
ER  -

Copy | Download