Medicinal plants have been utilized for centuries and continue to be a global resource for healthcare. They offer a potentially safer and more cost-effective alternative to conventional pharmaceuticals, which can pose health risks and financial burdens, especially in low-income communities. This study investigated the antimicrobial properties of Platycerium coronarium leaf extracts against Staphylococcus aureus and Escherichia coli. The extraction process involved maceration with methanol, ethanol, and chloroform solvents. Each extract was independently tested for antibacterial activity using the agar well diffusion method. Qualitative phytochemical analysis was conducted, revealing the presence of saponins, flavonoids, alkaloids, and glycosides in the methanol and ethanol extracts. Minimum Inhibitory Concentration (MIC) values were determined for the methanol extract against S. aureus. Results indicate that the methanol extract exhibited the highest antimicrobial activity (8.5mm) against S. aureus, followed by the ethanol extract (7mm), while the chloroform extract showed no antimicrobial effect. None of the extracts showed antimicrobial activity against E. coli. These findings suggest that Platycerium coronarium leaf extracts hold promise as natural antimicrobial agents. Further research, including in vivo studies, is required to evaluate their efficacy, safety, and mechanism of action against Gram-positive bacterial infections. Such investigations could contribute to the development of affordable alternatives to combat antibiotic resistance and alleviate medication costs in underserved communities.
| Published in | Journal of Diseases and Medicinal Plants (Volume 9, Issue 4) |
| DOI | 10.11648/j.jdmp.20230904.13 |
| Page(s) | 137-147 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Medicinal Plants, Antimicrobial Properties, Staphylococcus aureus, Escherichia coli, MIC
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APA Style
Robert, A., Isaac, I., Joel, W. (2023). Phytochemistry and Antibacterial Activity of Platycerium coronarium (Tanduk Rasa Fern) Leaf Extracts. Journal of Diseases and Medicinal Plants, 9(4), 137-147. https://doi.org/10.11648/j.jdmp.20230904.13
ACS Style
Robert, A.; Isaac, I.; Joel, W. Phytochemistry and Antibacterial Activity of Platycerium coronarium (Tanduk Rasa Fern) Leaf Extracts. J. Dis. Med. Plants 2023, 9(4), 137-147. doi: 10.11648/j.jdmp.20230904.13
AMA Style
Robert A, Isaac I, Joel W. Phytochemistry and Antibacterial Activity of Platycerium coronarium (Tanduk Rasa Fern) Leaf Extracts. J Dis Med Plants. 2023;9(4):137-147. doi: 10.11648/j.jdmp.20230904.13
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Download@article{10.11648/j.jdmp.20230904.13,
author = {Alule Robert and Isabirye Isaac and Walugembe Joel},
title = {Phytochemistry and Antibacterial Activity of Platycerium coronarium (Tanduk Rasa Fern) Leaf Extracts},
journal = {Journal of Diseases and Medicinal Plants},
volume = {9},
number = {4},
pages = {137-147},
doi = {10.11648/j.jdmp.20230904.13},
url = {https://doi.org/10.11648/j.jdmp.20230904.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20230904.13},
abstract = {Medicinal plants have been utilized for centuries and continue to be a global resource for healthcare. They offer a potentially safer and more cost-effective alternative to conventional pharmaceuticals, which can pose health risks and financial burdens, especially in low-income communities. This study investigated the antimicrobial properties of Platycerium coronarium leaf extracts against Staphylococcus aureus and Escherichia coli. The extraction process involved maceration with methanol, ethanol, and chloroform solvents. Each extract was independently tested for antibacterial activity using the agar well diffusion method. Qualitative phytochemical analysis was conducted, revealing the presence of saponins, flavonoids, alkaloids, and glycosides in the methanol and ethanol extracts. Minimum Inhibitory Concentration (MIC) values were determined for the methanol extract against S. aureus. Results indicate that the methanol extract exhibited the highest antimicrobial activity (8.5mm) against S. aureus, followed by the ethanol extract (7mm), while the chloroform extract showed no antimicrobial effect. None of the extracts showed antimicrobial activity against E. coli. These findings suggest that Platycerium coronarium leaf extracts hold promise as natural antimicrobial agents. Further research, including in vivo studies, is required to evaluate their efficacy, safety, and mechanism of action against Gram-positive bacterial infections. Such investigations could contribute to the development of affordable alternatives to combat antibiotic resistance and alleviate medication costs in underserved communities.
},
year = {2023}
}
TY - JOUR T1 - Phytochemistry and Antibacterial Activity of Platycerium coronarium (Tanduk Rasa Fern) Leaf Extracts AU - Alule Robert AU - Isabirye Isaac AU - Walugembe Joel Y1 - 2023/11/29 PY - 2023 N1 - https://doi.org/10.11648/j.jdmp.20230904.13 DO - 10.11648/j.jdmp.20230904.13 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 137 EP - 147 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.20230904.13 AB - Medicinal plants have been utilized for centuries and continue to be a global resource for healthcare. They offer a potentially safer and more cost-effective alternative to conventional pharmaceuticals, which can pose health risks and financial burdens, especially in low-income communities. This study investigated the antimicrobial properties of Platycerium coronarium leaf extracts against Staphylococcus aureus and Escherichia coli. The extraction process involved maceration with methanol, ethanol, and chloroform solvents. Each extract was independently tested for antibacterial activity using the agar well diffusion method. Qualitative phytochemical analysis was conducted, revealing the presence of saponins, flavonoids, alkaloids, and glycosides in the methanol and ethanol extracts. Minimum Inhibitory Concentration (MIC) values were determined for the methanol extract against S. aureus. Results indicate that the methanol extract exhibited the highest antimicrobial activity (8.5mm) against S. aureus, followed by the ethanol extract (7mm), while the chloroform extract showed no antimicrobial effect. None of the extracts showed antimicrobial activity against E. coli. These findings suggest that Platycerium coronarium leaf extracts hold promise as natural antimicrobial agents. Further research, including in vivo studies, is required to evaluate their efficacy, safety, and mechanism of action against Gram-positive bacterial infections. Such investigations could contribute to the development of affordable alternatives to combat antibiotic resistance and alleviate medication costs in underserved communities. VL - 9 IS - 4 ER -
Department of Biological Sciences, Faculty of Science, Kyambogo University, Kyambogo, Uganda
Department of Biological Sciences, Faculty of Science, Kyambogo University, Kyambogo, Uganda
Department of Biological Sciences, Faculty of Science, Kyambogo University, Kyambogo, Uganda
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