Background: Blue Nile State is one of the most health-fragile regions in Sudan, characterised by recurrent conflict, population displacement, poverty, weak health infrastructure, and a high burden of preventable communicable diseases. Despite its public health importance, state-level statistical evidence on disease burden and determinants of maternal and child health outcomes remains limited. Objective: This study aimed to describe the public health burden in Blue Nile State during 2010-2023 and to identify key statistical determinants associated with maternal and child mortality using available secondary data. Methods: A secondary data analysis was conducted using publicly available reports and published studies from WHO, UNICEF, OCHA, the Sudan Central Bureau of Statistics, the Federal and State Ministries of Health, and peer-reviewed literature. Descriptive statistics, comparative analysis against national averages and SDG targets, chi-square tests, t-tests, time-trend analysis, and multiple linear regression were applied. Regression assumptions were evaluated using residual diagnostics, variance inflation factors (VIF), Durbin-Watson statistics, and influence diagnostics. Results: Blue Nile State showed substantially poorer health indicators than national averages. The maternal mortality ratio (MMR) was estimated at 412 per 100,000 live births compared with 295 nationally, while the under-five mortality rate (U5MR) reached 89.3 per 1,000 live births compared with 56.0 nationally. Malaria represented the dominant communicable disease burden (68 cases per 1,000 population). The multiple linear regression model identified poverty rate, distance to health facility, maternal education, vaccination coverage, and malaria prevalence as statistically significant determinants (R2 = 0.784; F = 68.32; p < 0.001). Conclusion: Poor health outcomes in Blue Nile State are associated with structural deprivation, geographic barriers, infectious disease burden, limited vaccination coverage, and conflict-related disruption of health services. A comprehensive multi-sector strategy is urgently needed.
| Published in | Medicine and Life Sciences (Volume 2, Issue 3) |
| DOI | 10.11648/j.mls.20260203.11 |
| Page(s) | 59-73 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2026. Published by Science Publishing Group |
Blue Nile State, Sudan, Public Health, Maternal Mortality, Child Mortality, Malaria, Health Systems, Secondary Data Analysis, Regression Modelling
| [1] | United Nations Office for the Coordination of Humanitarian Affairs (OCHA). Sudan Humanitarian Situation Report 2023. Geneva: OCHA; 2023. |
| [2] | Doctors Without Borders (Médecins Sans Frontières, MSF). Blue Nile State: Health in Crisis. Brussels: MSF International; 2022. |
| [3] | Elnakib S, Yousif MK, Abdelwahab MM. Health system challenges in conflict-affected Sudan: A scoping review. Confl Health. 2021; 15(1): 45. |
| [4] | World Health Organization (WHO). Sudan Health Profile 2022. Geneva: WHO; 2022. |
| [5] | UNICEF. Sudan Humanitarian Action for Children 2023. New York: UNICEF; 2023. |
| [6] | Sudan Central Bureau of Statistics. Sudan Population Estimates 2023. Khartoum: CBS; 2023. |
| [7] | Hair JF, Black WC, Babin BJ, Anderson RE. Multivariate Data Analysis. 8th ed. Cengage Learning; 2019. |
| [8] | Field A. Discovering Statistics Using IBM SPSS Statistics. 5th ed. London: SAGE Publications; 2018. |
| [9] | UNICEF. State of the World’s Children 2023: Statistical Annexes. New York: UNICEF; 2023. |
| [10] | World Health Organization (WHO). Trends in Maternal Mortality 2000-2020. Geneva: WHO; 2023. |
| [11] | Hosmer DW, Lemeshow S, Sturdivant RX. Applied Logistic Regression. 3rd ed. Hoboken: Wiley; 2013. |
| [12] | Pantuliano S, Wekesa M. Improving health outcomes in fragile states: Experience in Sudan. HPG Policy Brief 36. London: ODI; 2008. |
| [13] | Young H, Osman AM, Aklilu Y, Dale R, Badri B. Darfur — Livelihoods Under Siege. Medford: Tufts University; 2005. |
| [14] | de Waal A. Sudan: The Turbulent State. London: Hurst; 2007. |
| [15] | Verhoeven H. Water, Civilisation and Power in Sudan. Cambridge University Press; 2015. |
| [16] | Mahmoud I, Kheirallah K. Impact of political instability on health system performance in Sudan. East Mediterr Health J. 2022; 28(3): 201-9. |
| [17] | Elhassan EM, Adam I. Conflict and health in Sudan: A review. Sudan J Paediatrics. 2021; 21(1): 4-11. |
| [18] | Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, et al. Global causes of maternal death: A WHO systematic analysis. Lancet Glob Health. 2014; 2(6): e323-33. |
| [19] | Graham WJ, Bell JS, Bullough CHW. Can skilled attendance at delivery reduce maternal mortality in developing countries? In: De Brouwere V, Van Lerberghe W (eds). Safe Motherhood Strategies. Antwerp: ITG Press; 2001. |
| [20] | Akbari M, Forooshani AR, Farsar AR, Kamalian A. Maternal mortality in conflict-affected settings: A systematic review. BMC Pregnancy Childbirth. 2022; 22: 312. |
| [21] | United Nations. Transforming Our World: The 2030 Agenda for Sustainable Development. New York: UN; 2015. |
| [22] | You D, Hug L, Ejdemyr S, Idele P, Hogan D, Mathers C, et al. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015. Lancet. 2015; 386(10010): 2275-86. |
| [23] | World Health Organization (WHO). World Malaria Report 2023. Geneva: WHO; 2023. |
| [24] | Desai M, ter Kuile FO, Nosten F, McGready R, Asamoa K, Brabin B, et al. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis. 2007; 7(2): 93-104. |
| [25] | Black RE, Victora CG, Walker SP, Bhutta ZA, Christian P, de Onis M, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013; 382(9890): 427-51. |
| [26] | Prüss-Ustün A, Wolf J, Corvalán C, Bos R, Neira M. Preventing Disease Through Healthy Environments. Geneva: WHO; 2016. |
| [27] | Kruk ME, Gage AD, Joseph NT, Danaei G, García-Saisó S, Salomon JA. Mortality due to low-quality health systems in the universal health coverage era. Lancet. 2018; 392(10160): 2203-12. |
| [28] | Murray CJL, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, et al. Disability-adjusted life years for 291 diseases and injuries in 21 regions. Lancet. 2013; 380(9859): 2197-223. |
| [29] | Rao JNK, Molina I. Small Area Estimation. 2nd ed. Hoboken: Wiley; 2015. |
| [30] | Victora CG, Habicht JP, Bryce J. Evidence-based public health: Moving beyond randomized trials. Am J Public Health. 2004; 94(3): 400-5. |
| [31] | Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al. Meta-analysis of observational studies in epidemiology. JAMA. 2000; 283(15): 2008-12. |
| [32] | International Organization for Migration (IOM). Displacement Tracking Matrix: Sudan Report 2023. Geneva: IOM; 2023. |
| [33] | AbouZahr C, Boerma T. Health information systems: The foundations of public health. Bull World Health Organ. 2005; 83(8): 578-83. |
| [34] | Hotchkiss DR, Rous JJ, Karmacharya K, Sangraula P. Household health expenditures in Nepal: Implications for health care financing reform. Health Policy Plan. 1998; 13(4): 371-83. |
| [35] | Victora CG, Barros AJ, Axelson H, Bhutta ZA, Chopra M, França GV, et al. How changes in coverage affect equity in maternal and child health interventions in 35 Countdown to 2015 countries: An analysis of national surveys. Lancet. 2012; 380(9848): 1149-56. |
| [36] | Gwatkin DR, Rutstein S, Johnson K, Suliman EA, Wagstaff A, Amouzou A. Socio-economic Differences in Health, Nutrition, and Population in Developing Countries. Washington DC: World Bank; 2007. |
| [37] | Al Zahrani S, Al Sameeh FAR, Musa ACM, Shokeralla AA. Forecasting diabetes patients attendance at Al-Baha hospitals using autoregressive fractional integrated moving average (ARFIMA) models. Journal of Data Analysis and Information Processing 2020; 8: 183-194. |
| [38] | Daqqa I, Almarashi AM, Bashier MM, Aripov M, Abaker AOI, Alhag AA, Shokeralla AA. Predictive modeling of breast cancer incidence: A comparative study of fuzzy time series and machine learning techniques. Journal of Statistics Applications & Probability 2025; 14(2): 183-189. |
| [39] | Gubara, H. M., & Shokeralla, A. A. (2021). Mellin transform of Mittag-Leffler density and its relationship with some special functions. International Journal of Research in Engineering and Science (IJRES), 9(3), 8-13. |
| [40] | Saber, S., Alahmari, A., Shokeralla, A. A., & EL Guma, F. (2025). Numerical techniques for solving fractional glucose-insulin regulatory systems. Lobachevskii Journal of Mathematics, 46(10), 5471-5483. |
| [41] | R. Saadeh, A. A. Shokeralla, N. Al-Kuleab, W. S. Hamad, M. Ali, M. A. Abdoon, and F. El Guma. Stochastic modelling of seasonal influenza dynamics: Integrating random perturbations and behavioural factors. European Journal of Pure and Applied Mathematics, 18(3): 6379, 2025. |
| [42] | Shokeralla AA, Qurashi ME, Mekki RY, Ali MS. The effect of symptoms on the survival time of coronavirus patients in the Sudanese population. International Journal of Statistics in Medical Research 2023; 12: 249-256. |
| [43] | Ali, M. S., Abd Elmotaleb, A. M. A., Shokeralla, A. A., & Elamin, M. (2023). A novel formula for solving integral transforms. Applied Mathematics & Information Sciences, 17(6), 1171-1175. |
| [44] | Fath-Elrhman EI, Abdelaziz GMM, Shokeralla AA, Alzahrani S. Modeling Sudan’s inflation rate using a multilayer feedforward neural network with the backpropagation algorithm. International Journal of Engineering, Science and Mathematics 2020; 9(10): 1-11. |
| [45] |
Shokeralla, A. A. (2025). A Comparative Analysis of NNAR and LSTM Models for Short-Term COVID-19 Forecasting in Saudi Arabia. International Journal of Soft Computing and Engineering (IJSCE), 15(2), 31-39.
https://www.ijsce.org/wp-content/uploads/papers/v15i2/B365715020525.pdf |
| [46] | Abdulaziz, G. M., Faith, A. A. S., Ashaikh, A. A., & Salem, A. Z. (2020). A transfer function technique for moeling Sudanese agricultural exports. International Journal of Current Research, 12(9), 13699-13705. |
| [47] | Shokeralla, A. A. (2025). The discrete Laplace transform (DLT) order: A sensitive approach to comparing discrete residual life distributions with applications to queueing systems. European Journal of Pure and Applied Mathematics, 18, 6994. |
| [48] | Saadeh, R., Al-Kuleab, N., El Guma, F., Shokeralla, A. A., Abdalla, S. J. M., Abdoon, M. A., & Hafez, M. (2026). Bayesian inference for modeling seasonal influenza transmission under control measures. Results in Control and Optimization, 23, 100714. |
| [49] | Abbas, S. M., Ijaz, R., Hussain, T., Haider, M. W., Nafees, M., Stanciu, A. S.,. & Rzayeva, A. (2026). Plant spacing modulates growth, yield and nutrient dynamics of sponge gourd under semi-arid conditions. Scientific Reports. |
| [50] | Alahmadi, R. M., Awadalla, M., Saeed, B., Alshanbari, H. M., Shokeralla, A. A., Yassin, A. A., Alosaimi, B., & El Guma, F. (2026). A hybrid STL-LightGBM framework with probabilistic forecasting for Influenza A incidence in the post-pandemic Saudi Arabia. Frontiers in Public Health, 14, 1803353. |
| [51] | El Guma, F., Awadalla, M., Al Rawi, H. Z., Saeed, B., Alshanbari, H. M., Shokeralla, A. A., & Alosaimi, B. (2026). Early-warning prediction of visceral leishmaniasis mortality using a multivariate STL-deep learning hybrid approach on 20 years of monthly time series. Frontiers in Public Health, 14, 1754966. |
| [52] | El Guma, F., Ali, A. Y., Eltaweel, M. A. M., Musa, R. A., & Shokeralla, A. A. (2026). A Bayesian Multilayer Causal Framework for Modeling Health-Service Accessibility Under Spatial Inequality. Letters in Biomathematics, 13(1), 15-26. |
| [53] | Shokeralla, A. A. (2025). Modeling Bitcoin price dynamics using a fractional Maxwell-Weibull copula distribution. International Journal of Neutrosophic Science, 26(4), 309-326. |
| [54] | Shokeralla, A. A. (2025). A hybrid time series-regression model for tuberculosis forecasting in resource-limited settings. International Journal of Statistics in Medical Research, 14, 299-307. |
| [55] | Shokeralla, A. A., El Guma, F., Abdalla, A. H., Hagsddig, A. E., Musa, R. A., Eltaweel, M. A. M., Elawad, A. H., & Elshamy, I. (2025). Machine learning-based prediction of seasonal influenza trends in Saudi Arabia: A tool for regional public health planning. International Journal of Statistics in Medical Research, 14, 688-696. |
| [56] | Bezerra AKL, Santos ÉMC. Prediction of the daily number of confirmed cases of COVID-19 in Sudan with ARIMA and Holt-Winters exponential smoothing. International Journal of Development Research 2020; 10(8): 39408-39413 |
| [57] | Shokeralla, A. A., Alzharani, A. A., Abdalla, A. H., Modawy, Y. M., Elshamy, I., & El Guma, F. (2025). Modeling climate-driven cholera outbreaks: A negative binomial regression framework with improved handling of overdispersion and extreme events. Letters in Biomathematics, 12(1). |
| [58] |
Gubara, H. M., Shokeralla, A. A., & Ali, M. S. (2021). Orthogonality of some related polynomials to three-parameter Mittag-Leffler function. Journal of Research in Applied Mathematics, 7(1), 1-4.
https://www.questjournals.org/jram/papers/v7-i1/A07010104.pdf |
| [59] | Pelletier DL, Frongillo EA, Schroeder DG, Habicht JP. The effects of malnutrition on child mortality in developing countries. Bull World Health Organ. 1995; 73(4): 443-8. |
| [60] | World Health Organization (WHO). Global Vaccine Action Plan 2011-2020. Geneva: WHO; 2013. |
APA Style
Shokeralla, A. A., Alshaib, M. A., Daif, W. A. (2026). Public Health Burden and Statistical Determinants of Maternal and Child Mortality in Blue Nile State, Sudan: A Secondary Data Analysis, 2010-2023. Medicine and Life Sciences, 2(3), 59-73. https://doi.org/10.11648/j.mls.20260203.11
ACS Style
Shokeralla, A. A.; Alshaib, M. A.; Daif, W. A. Public Health Burden and Statistical Determinants of Maternal and Child Mortality in Blue Nile State, Sudan: A Secondary Data Analysis, 2010-2023. Med. Life Sci. 2026, 2(3), 59-73. doi: 10.11648/j.mls.20260203.11
AMA Style
Shokeralla AA, Alshaib MA, Daif WA. Public Health Burden and Statistical Determinants of Maternal and Child Mortality in Blue Nile State, Sudan: A Secondary Data Analysis, 2010-2023. Med Life Sci. 2026;2(3):59-73. doi: 10.11648/j.mls.20260203.11
@article{10.11648/j.mls.20260203.11,
author = {Alshaikh Ahmed Shokeralla and Mohammed Ali Alshaib and Waleid Alnour Daif},
title = {Public Health Burden and Statistical Determinants of Maternal and Child Mortality in Blue Nile State, Sudan:
A Secondary Data Analysis, 2010-2023},
journal = {Medicine and Life Sciences},
volume = {2},
number = {3},
pages = {59-73},
doi = {10.11648/j.mls.20260203.11},
url = {https://doi.org/10.11648/j.mls.20260203.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mls.20260203.11},
abstract = {Background: Blue Nile State is one of the most health-fragile regions in Sudan, characterised by recurrent conflict, population displacement, poverty, weak health infrastructure, and a high burden of preventable communicable diseases. Despite its public health importance, state-level statistical evidence on disease burden and determinants of maternal and child health outcomes remains limited. Objective: This study aimed to describe the public health burden in Blue Nile State during 2010-2023 and to identify key statistical determinants associated with maternal and child mortality using available secondary data. Methods: A secondary data analysis was conducted using publicly available reports and published studies from WHO, UNICEF, OCHA, the Sudan Central Bureau of Statistics, the Federal and State Ministries of Health, and peer-reviewed literature. Descriptive statistics, comparative analysis against national averages and SDG targets, chi-square tests, t-tests, time-trend analysis, and multiple linear regression were applied. Regression assumptions were evaluated using residual diagnostics, variance inflation factors (VIF), Durbin-Watson statistics, and influence diagnostics. Results: Blue Nile State showed substantially poorer health indicators than national averages. The maternal mortality ratio (MMR) was estimated at 412 per 100,000 live births compared with 295 nationally, while the under-five mortality rate (U5MR) reached 89.3 per 1,000 live births compared with 56.0 nationally. Malaria represented the dominant communicable disease burden (68 cases per 1,000 population). The multiple linear regression model identified poverty rate, distance to health facility, maternal education, vaccination coverage, and malaria prevalence as statistically significant determinants (R2 = 0.784; F = 68.32; p < 0.001). Conclusion: Poor health outcomes in Blue Nile State are associated with structural deprivation, geographic barriers, infectious disease burden, limited vaccination coverage, and conflict-related disruption of health services. A comprehensive multi-sector strategy is urgently needed.},
year = {2026}
}
TY - JOUR T1 - Public Health Burden and Statistical Determinants of Maternal and Child Mortality in Blue Nile State, Sudan: A Secondary Data Analysis, 2010-2023 AU - Alshaikh Ahmed Shokeralla AU - Mohammed Ali Alshaib AU - Waleid Alnour Daif Y1 - 2026/07/27 PY - 2026 N1 - https://doi.org/10.11648/j.mls.20260203.11 DO - 10.11648/j.mls.20260203.11 T2 - Medicine and Life Sciences JF - Medicine and Life Sciences JO - Medicine and Life Sciences SP - 59 EP - 73 PB - Science Publishing Group SN - 3071-0618 UR - https://doi.org/10.11648/j.mls.20260203.11 AB - Background: Blue Nile State is one of the most health-fragile regions in Sudan, characterised by recurrent conflict, population displacement, poverty, weak health infrastructure, and a high burden of preventable communicable diseases. Despite its public health importance, state-level statistical evidence on disease burden and determinants of maternal and child health outcomes remains limited. Objective: This study aimed to describe the public health burden in Blue Nile State during 2010-2023 and to identify key statistical determinants associated with maternal and child mortality using available secondary data. Methods: A secondary data analysis was conducted using publicly available reports and published studies from WHO, UNICEF, OCHA, the Sudan Central Bureau of Statistics, the Federal and State Ministries of Health, and peer-reviewed literature. Descriptive statistics, comparative analysis against national averages and SDG targets, chi-square tests, t-tests, time-trend analysis, and multiple linear regression were applied. Regression assumptions were evaluated using residual diagnostics, variance inflation factors (VIF), Durbin-Watson statistics, and influence diagnostics. Results: Blue Nile State showed substantially poorer health indicators than national averages. The maternal mortality ratio (MMR) was estimated at 412 per 100,000 live births compared with 295 nationally, while the under-five mortality rate (U5MR) reached 89.3 per 1,000 live births compared with 56.0 nationally. Malaria represented the dominant communicable disease burden (68 cases per 1,000 population). The multiple linear regression model identified poverty rate, distance to health facility, maternal education, vaccination coverage, and malaria prevalence as statistically significant determinants (R2 = 0.784; F = 68.32; p < 0.001). Conclusion: Poor health outcomes in Blue Nile State are associated with structural deprivation, geographic barriers, infectious disease burden, limited vaccination coverage, and conflict-related disruption of health services. A comprehensive multi-sector strategy is urgently needed. VL - 2 IS - 3 ER -