The Strychnos spinosa seeds contains eriocitrin and neoericitrin which were potential antioxidant molecules. In addition, it contains ursolic acid, lupeol, teraxerol and β-sitosterol which were potential anti-inflammatory molecules. These molecules were extracted from the Strychnos spinosa seeds by esterification with citric acid moles as described in the bibliography in order to synthesize the citric acid ester of Strychnos spinosa seeds. Thus, in this manuscript, the potentiality of this ester solution to be an antioxidant and anti-inflammatory was tested using the spectrophotometry UV-visible method at the wavelength respectively λ=517[nm] and λ=550[nm] according to procedures described in this manuscript. For all tests, a principal-source solution was prepared using the citric acid ester of Strychnos spinosa seeds solution and appropriate solvents; thus from this solution was prepared the solutions at different concentrations to be tested. It was noticed that the concentration ratio between the active molecules and the molecules reacting with these active molecules during the antioxidant and anti-inflammatory tests influenced the quality of the tests. Thus, it was deduced that a low ratio allowed to a better quality results during the spectrophotometer UV-visible antioxidant and anti-inflammatory tests. In consequence, the quantities of the active molecules in the citric acid ester of Strychnos spinosa seeds necessary to the fifty percent diminution of the reacting or formed chemical molecules according to the tests respectively antioxidant tests or anti-inflammatory tests noted Ic-50 were deduced and allowed to evaluate and to compare their activities.
| Published in | American Journal of Applied Chemistry (Volume 11, Issue 6) |
| DOI | 10.11648/j.ajac.20231106.11 |
| Page(s) | 137-145 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Strychnos spinosa’s Seeds, Flavonoids, Steroids, Antioxidant, Anti-Inflammatory, Ic-50
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APA Style
Rabeharitsara, A. T., Raharimalala, M. F., Tsiresy, D. A. F., Robijaona, B., Pierre, R., et al. (2023). Antioxidant and Anti-Inflammatory Activities of the Strychnos spinosa Seeds’ Citric Acid Esters Solution. American Journal of Applied Chemistry, 11(6), 137-145. https://doi.org/10.11648/j.ajac.20231106.11
ACS Style
Rabeharitsara, A. T.; Raharimalala, M. F.; Tsiresy, D. A. F.; Robijaona, B.; Pierre, R., et al. Antioxidant and Anti-Inflammatory Activities of the Strychnos spinosa Seeds’ Citric Acid Esters Solution. Am. J. Appl. Chem. 2023, 11(6), 137-145. doi: 10.11648/j.ajac.20231106.11
AMA Style
Rabeharitsara AT, Raharimalala MF, Tsiresy DAF, Robijaona B, Pierre R, et al. Antioxidant and Anti-Inflammatory Activities of the Strychnos spinosa Seeds’ Citric Acid Esters Solution. Am J Appl Chem. 2023;11(6):137-145. doi: 10.11648/j.ajac.20231106.11
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Download@article{10.11648/j.ajac.20231106.11,
author = {Andry Tahina Rabeharitsara and Marie Florence Raharimalala and Diary Andriamanana Faharetana Tsiresy and Baholy Robijaona and Rakotomamonjy Pierre and Hanitriniaina Marie Ratsimba},
title = {Antioxidant and Anti-Inflammatory Activities of the Strychnos spinosa Seeds’ Citric Acid Esters Solution},
journal = {American Journal of Applied Chemistry},
volume = {11},
number = {6},
pages = {137-145},
doi = {10.11648/j.ajac.20231106.11},
url = {https://doi.org/10.11648/j.ajac.20231106.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231106.11},
abstract = {The Strychnos spinosa seeds contains eriocitrin and neoericitrin which were potential antioxidant molecules. In addition, it contains ursolic acid, lupeol, teraxerol and β-sitosterol which were potential anti-inflammatory molecules. These molecules were extracted from the Strychnos spinosa seeds by esterification with citric acid moles as described in the bibliography in order to synthesize the citric acid ester of Strychnos spinosa seeds. Thus, in this manuscript, the potentiality of this ester solution to be an antioxidant and anti-inflammatory was tested using the spectrophotometry UV-visible method at the wavelength respectively λ=517[nm] and λ=550[nm] according to procedures described in this manuscript. For all tests, a principal-source solution was prepared using the citric acid ester of Strychnos spinosa seeds solution and appropriate solvents; thus from this solution was prepared the solutions at different concentrations to be tested. It was noticed that the concentration ratio between the active molecules and the molecules reacting with these active molecules during the antioxidant and anti-inflammatory tests influenced the quality of the tests. Thus, it was deduced that a low ratio allowed to a better quality results during the spectrophotometer UV-visible antioxidant and anti-inflammatory tests. In consequence, the quantities of the active molecules in the citric acid ester of Strychnos spinosa seeds necessary to the fifty percent diminution of the reacting or formed chemical molecules according to the tests respectively antioxidant tests or anti-inflammatory tests noted Ic-50 were deduced and allowed to evaluate and to compare their activities.
},
year = {2023}
}
TY - JOUR T1 - Antioxidant and Anti-Inflammatory Activities of the Strychnos spinosa Seeds’ Citric Acid Esters Solution AU - Andry Tahina Rabeharitsara AU - Marie Florence Raharimalala AU - Diary Andriamanana Faharetana Tsiresy AU - Baholy Robijaona AU - Rakotomamonjy Pierre AU - Hanitriniaina Marie Ratsimba Y1 - 2023/11/11 PY - 2023 N1 - https://doi.org/10.11648/j.ajac.20231106.11 DO - 10.11648/j.ajac.20231106.11 T2 - American Journal of Applied Chemistry JF - American Journal of Applied Chemistry JO - American Journal of Applied Chemistry SP - 137 EP - 145 PB - Science Publishing Group SN - 2330-8745 UR - https://doi.org/10.11648/j.ajac.20231106.11 AB - The Strychnos spinosa seeds contains eriocitrin and neoericitrin which were potential antioxidant molecules. In addition, it contains ursolic acid, lupeol, teraxerol and β-sitosterol which were potential anti-inflammatory molecules. These molecules were extracted from the Strychnos spinosa seeds by esterification with citric acid moles as described in the bibliography in order to synthesize the citric acid ester of Strychnos spinosa seeds. Thus, in this manuscript, the potentiality of this ester solution to be an antioxidant and anti-inflammatory was tested using the spectrophotometry UV-visible method at the wavelength respectively λ=517[nm] and λ=550[nm] according to procedures described in this manuscript. For all tests, a principal-source solution was prepared using the citric acid ester of Strychnos spinosa seeds solution and appropriate solvents; thus from this solution was prepared the solutions at different concentrations to be tested. It was noticed that the concentration ratio between the active molecules and the molecules reacting with these active molecules during the antioxidant and anti-inflammatory tests influenced the quality of the tests. Thus, it was deduced that a low ratio allowed to a better quality results during the spectrophotometer UV-visible antioxidant and anti-inflammatory tests. In consequence, the quantities of the active molecules in the citric acid ester of Strychnos spinosa seeds necessary to the fifty percent diminution of the reacting or formed chemical molecules according to the tests respectively antioxidant tests or anti-inflammatory tests noted Ic-50 were deduced and allowed to evaluate and to compare their activities. VL - 11 IS - 6 ER -
Chemical Process Engineering Department (E. S. P. A), Antananarivo University, Antananarivo, Madagascar
Chemical Process Engineering Department (E. S. P. A), Antananarivo University, Antananarivo, Madagascar
Chemical Process Engineering Department (E. S. P. A), Antananarivo University, Antananarivo, Madagascar
Chemical Process Engineering Department (E. S. P. A), Antananarivo University, Antananarivo, Madagascar
Chemical Process Engineering Department (E. S. P. A), Antananarivo University, Antananarivo, Madagascar
Chemical Process Engineering Department (E. S. P. A), Antananarivo University, Antananarivo, Madagascar
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