Background: To better understand the frequency of E. coli and Klebsiella spp. among patients with urinary tract infections at the University of Benin Teaching Hospital, Benin City. Objective: This study aimed to analyze their patterns of antibiotic resistance. Methods: The Kirby-Bauer disk-diffusion method was employed to test the susceptibility of various microbes. Results: E. coli was the most prevalent pathogen in this study's 50 samples, with a prevalence of 64%, followed by Klebsiella spp. with a prevalence of 36%. Escherichia coli isolates were highly susceptible to imipenem (75%) and nitrofurantoin (65.6%), but showed high resistance to cefotaxime (100%), amoxicillin-clavulanate acid (100%), and nalidixic acid (96.9%). Klebsiella spp isolates were highly susceptible to Imipenem (50%) but showed 100% resistance to amoxicillin-clavulanate acid and cefotaxime, respectively. Therefore, these results should form the basis for preliminary decision-making about the best course of treatment for urinary tract infections (UTIs). Conclusion: This study demonstrated that the effectiveness of UTI therapy using available antibiotics is limited due to the increasing prevalence of antibiotic-resistant uropathogens.
| Published in | International Journal of Biomedical Science and Engineering (Volume 14, Issue 1) |
| DOI | 10.11648/j.ijbse.20261401.12 |
| Page(s) | 14-21 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2026. Published by Science Publishing Group |
Escherichia Coli, Klebsiella Spp, Urinary Tract Infection (UTI)
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APA Style
Isaiah, O. O. (2026). Antimicrobial Resistance Pattern of Escherichia Coli (E. coli) and Klebsiella Spp Isolated from Patients with Urinary Tract Infection. International Journal of Biomedical Science and Engineering, 14(1), 14-21. https://doi.org/10.11648/j.ijbse.20261401.12
ACS Style
Isaiah, O. O. Antimicrobial Resistance Pattern of Escherichia Coli (E. coli) and Klebsiella Spp Isolated from Patients with Urinary Tract Infection. Int. J. Biomed. Sci. Eng. 2026, 14(1), 14-21. doi: 10.11648/j.ijbse.20261401.12
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Download@article{10.11648/j.ijbse.20261401.12,
author = {Ogunsina Olabode Isaiah},
title = {Antimicrobial Resistance Pattern of Escherichia Coli (E. coli) and Klebsiella Spp Isolated from Patients with Urinary Tract Infection},
journal = {International Journal of Biomedical Science and Engineering},
volume = {14},
number = {1},
pages = {14-21},
doi = {10.11648/j.ijbse.20261401.12},
url = {https://doi.org/10.11648/j.ijbse.20261401.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20261401.12},
abstract = {Background: To better understand the frequency of E. coli and Klebsiella spp. among patients with urinary tract infections at the University of Benin Teaching Hospital, Benin City. Objective: This study aimed to analyze their patterns of antibiotic resistance. Methods: The Kirby-Bauer disk-diffusion method was employed to test the susceptibility of various microbes. Results: E. coli was the most prevalent pathogen in this study's 50 samples, with a prevalence of 64%, followed by Klebsiella spp. with a prevalence of 36%. Escherichia coli isolates were highly susceptible to imipenem (75%) and nitrofurantoin (65.6%), but showed high resistance to cefotaxime (100%), amoxicillin-clavulanate acid (100%), and nalidixic acid (96.9%). Klebsiella spp isolates were highly susceptible to Imipenem (50%) but showed 100% resistance to amoxicillin-clavulanate acid and cefotaxime, respectively. Therefore, these results should form the basis for preliminary decision-making about the best course of treatment for urinary tract infections (UTIs). Conclusion: This study demonstrated that the effectiveness of UTI therapy using available antibiotics is limited due to the increasing prevalence of antibiotic-resistant uropathogens.},
year = {2026}
}
TY - JOUR T1 - Antimicrobial Resistance Pattern of Escherichia Coli (E. coli) and Klebsiella Spp Isolated from Patients with Urinary Tract Infection AU - Ogunsina Olabode Isaiah Y1 - 2026/01/27 PY - 2026 N1 - https://doi.org/10.11648/j.ijbse.20261401.12 DO - 10.11648/j.ijbse.20261401.12 T2 - International Journal of Biomedical Science and Engineering JF - International Journal of Biomedical Science and Engineering JO - International Journal of Biomedical Science and Engineering SP - 14 EP - 21 PB - Science Publishing Group SN - 2376-7235 UR - https://doi.org/10.11648/j.ijbse.20261401.12 AB - Background: To better understand the frequency of E. coli and Klebsiella spp. among patients with urinary tract infections at the University of Benin Teaching Hospital, Benin City. Objective: This study aimed to analyze their patterns of antibiotic resistance. Methods: The Kirby-Bauer disk-diffusion method was employed to test the susceptibility of various microbes. Results: E. coli was the most prevalent pathogen in this study's 50 samples, with a prevalence of 64%, followed by Klebsiella spp. with a prevalence of 36%. Escherichia coli isolates were highly susceptible to imipenem (75%) and nitrofurantoin (65.6%), but showed high resistance to cefotaxime (100%), amoxicillin-clavulanate acid (100%), and nalidixic acid (96.9%). Klebsiella spp isolates were highly susceptible to Imipenem (50%) but showed 100% resistance to amoxicillin-clavulanate acid and cefotaxime, respectively. Therefore, these results should form the basis for preliminary decision-making about the best course of treatment for urinary tract infections (UTIs). Conclusion: This study demonstrated that the effectiveness of UTI therapy using available antibiotics is limited due to the increasing prevalence of antibiotic-resistant uropathogens. VL - 14 IS - 1 ER -
Department of Public Health, College of Allied Health Science, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria;Department of Pharmacy, Dora Akunyili College of Pharmacy, Igbinedion University, Okada, Nigeria;Majestic Vistal Pharmaceutical Ltd, Community Pharmacy and Dispensing Department, Akure, Nigeria
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