Gangrenous Colitis in a Patient with Polypharmacy: A Case Study
Hassan Malik,
Sivananthan Suntharalingam,
Muhammad Majid Ali
Issue:
Volume 4, Issue 1, February 2016
Pages:
4-7
Received:
13 January 2016
Accepted:
25 January 2016
Published:
29 February 2016
Abstract: A 20-year-old female, otherwise fit and well, was admitted to intensive care unit intubated with polypharmacy secondary to drug over dose. She developed a seizure episode and a rise in serum lactate within 24 hours of admission, followed by abdominal distension, with metabolic acidosis and a further elevation of serum lactate levels. CT abdomen revealed gangrenous colitis, which was confirmed on laparotomy. The patient underwent subtotal colectomy with end ileostomy, which was further complicated a week later by necrosis of the stoma due to knotting of the small bowel around the ileostomy loop. She underwent another laparotomy, for fixation of internal herniation of small bowel loops as well re-fashioning of the end ileostomy, and had an uneventful recovery. Final pathology of the colon showed ischaemic colitis with mural necrosis, peritonitis and viable resection margins.
Abstract: A 20-year-old female, otherwise fit and well, was admitted to intensive care unit intubated with polypharmacy secondary to drug over dose. She developed a seizure episode and a rise in serum lactate within 24 hours of admission, followed by abdominal distension, with metabolic acidosis and a further elevation of serum lactate levels. CT abdomen rev...
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