Case Report
Presacral Ganglioneuroma in a 30-Year-Old Female: Case Report and Literature Review
Issue:
Volume 13, Issue 2, June 2025
Pages:
23-26
Received:
9 May 2025
Accepted:
3 June 2025
Published:
16 July 2025
Abstract: Background: Ganglioneuromas are rare, benign tumors derived from neural crest cells of the sympathetic nervous system. These tumors are typically found in the posterior mediastinum and retroperitoneum, and are characterized by well-differentiated ganglion and Schwann cells. Presacral ganglioneuromas are extremely uncommon, with few cases documented in the literature. Their rarity and nonspecific clinical presentation can pose diagnostic challenges. It is worth mentioning that there are few cases in the literature report ganglioneuroma in association with MEN type 2B. Case Presentation: We report the case of a 30-year-old female who presented with a three-month history of mild lower abdominal discomfort and non-radicular lower back pain. Her physical examination was unremarkable, and routine laboratory investigations, including tumor markers and catecholamine levels, were within normal limits. Initial ultrasonography was inconclusive. However, contrast-enhanced computed tomography (CT) revealed a well-circumscribed, 5 × 3 cm lesion in the presacral region, causing widening of the right middle sacral foramina. Magnetic resonance imaging (MRI) further characterized the mass as isointense on T1-weighted imaging and heterogeneously hyperintense on T2-weighted imaging, with peripheral enhancement after gadolinium administration. Given its location and imaging characteristics, the lesion was surgically excised via microscopic resection. The postoperative course was uneventful, and the patient was discharged in stable condition. Histopathologic analysis confirmed the diagnosis of ganglioneuroma, revealing mature ganglion cells embedded in a schwannian stroma with fibrous and edematous areas. Conclusion: This case underscores the importance of considering ganglioneuroma in the differential diagnosis of presacral masses. Timely imaging and surgical intervention are key to effective management and favorable outcomes. We present a rare case of a presacral ganglioneuroma in a 30-year-old female patient who experienced mild lower abdominal discomfort and non-radicular lower back pain over a three-month period, without significant neurological symptoms. Diagnostic imaging revealed a presacral lesion at the S2-3 level, leading to a surgical intervention that resulted in a subtotal excision of the mass. Histopathological analysis confirmed the diagnosis of ganglioneuroma. This case underscores the importance of considering presacral ganglioneuroma in the differential diagnosis of presacral lesions, given their subtle presentation and potential complications.
Abstract: Background: Ganglioneuromas are rare, benign tumors derived from neural crest cells of the sympathetic nervous system. These tumors are typically found in the posterior mediastinum and retroperitoneum, and are characterized by well-differentiated ganglion and Schwann cells. Presacral ganglioneuromas are extremely uncommon, with few cases documented...
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Research Article
Suicidal Ideation Factors and Coping Mechanisms Among Breast and Cervical Cancer Women in Harar, Ethiopia: A Qualitative Study
Aminu Mohammed Yasin*,
Bezabih Amsalu,
Neima Redwan Abdu,
Abduselam Yimer,
Hassen Mosa Helil,
Ahmedin Aliyi Usso
Issue:
Volume 13, Issue 2, June 2025
Pages:
27-35
Received:
27 January 2025
Accepted:
3 June 2025
Published:
31 July 2025
DOI:
10.11648/j.jctr.20251302.12
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Abstract: Background: Cancer-related suicidal ideations and coping mechanisms vary from country to country and region to region within a country. So, identifying these can help in interventions, thereby reducing suicidal risks, morbidity, and mortality. Purpose: The aim of this study was to explore suicidal ideation factors and coping mechanisms among breast and cervical cancer women in Harar, Ethiopia. Methods: A qualitative study was applied using an interview guide. The interviews were then transcribed verbatim and analyzed using an inductive thematic approach. The study was conducted in one large regional oncology center in Harar, Ethiopia. A purposive sample of 23 women (nine with cervical cancer and 14 with breast cancer) was individually interviewed, aided by a voice recorder and field notes between June and August 202023. Findings: Twenty-three women (nine with cervical cancer and 14 with breast cancer) were involved in the study. Six key suicidal ideation factors were explored, influenced by self-perception, family and society, income, cancer information, traditional healers, and witch doctors. Coping mechanisms included acceptance, religious practices, advice from friends, counseling from professionals, non-disclosure, and sports. Conclusion: Factors of suicidal ideation for cancer women (breast and cervical) emanated from self, family, society, income, and information, and they different coping mechanisms. Therefore, it is imperative to develop patient-family-societal, culturally sensitive, and inclusive programs that address factors contributing to suicide.
Abstract: Background: Cancer-related suicidal ideations and coping mechanisms vary from country to country and region to region within a country. So, identifying these can help in interventions, thereby reducing suicidal risks, morbidity, and mortality. Purpose: The aim of this study was to explore suicidal ideation factors and coping mechanisms among breast...
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,
Ayman Ahmad Salman
