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A Aggressive Osteosarcoma of Mandible with Lung Metastasis in a 5 Year Child: A Case Report
Govardhan H. B,
Satyajit Pradhan,
Rashmi Singh,
Prakash Swain,
Lalit Agarwal
Issue:
Volume 2, Issue 2, March 2014
Pages:
15-17
Received:
18 February 2014
Published:
10 March 2014
Abstract: Osteosarcoma is a malignant mesenchymal tumor whose cancerous cells produce osteoid matrix. It is the most common primary malignant bone tumor, accounting for approximately 20% of the sarcomas, but osteosarcoma of mandible is rare only 5% of the osteosarcomas occur in the jaws and occur mainly in adult population in their later part of the life. They present various clinical and histological aspects, as well as variable disease progression and outcome. Mandibular osteosarcoma are slow growing tumors and have better prognosis compared to other site. Lung is the most common site of metastasis in osteosarcoma mainly in the long bones, in craniofascial osteosarcoma lung metastasis is a rare findings. We are presenting a case of osteosarcoma of mandible in 5 year child with aggressive initial presentation.
Abstract: Osteosarcoma is a malignant mesenchymal tumor whose cancerous cells produce osteoid matrix. It is the most common primary malignant bone tumor, accounting for approximately 20% of the sarcomas, but osteosarcoma of mandible is rare only 5% of the osteosarcomas occur in the jaws and occur mainly in adult population in their later part of the life. T...
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Cultural and Environmental Factors of Triple-Negative Breast Carcinomas
Mackenzie Whitesell,
Sarah Al-Najar,
Gillian Bowser,
Mark A. Brown
Issue:
Volume 2, Issue 2, March 2014
Pages:
18-28
Received:
11 February 2014
Published:
10 March 2014
Abstract: Breast cancer is a leading cause of cancer death in the world. The triple-negative breast cancer subtype is associated with poorer prognosis than hormone receptor-positive subtypes and is more prevalent among African Americans than white, European Americans. The goal of this study has been to elucidate environmental, hormonal, and cultural factors that may be contributing to this disparity in an effort to identify modifiable risk factors and improve triple-negative breast cancer outcomes. Factors that may impact risk include vitamin D defiency, hormonal factors, environmental and dietary exposure, radiation exposure, and obesity. These factors may disproportionately affect African American women as a result of socioeconomic status, lifestyle, and cultural norms. Furthermore, disparities in prognosis may be compounded by barriers such as access to healthcare, prevention education, and perceptions of healthcare. Both biological and sociocultural factors impacting risk must be addressed in order for future prevention and treatment efforts to succeed.
Abstract: Breast cancer is a leading cause of cancer death in the world. The triple-negative breast cancer subtype is associated with poorer prognosis than hormone receptor-positive subtypes and is more prevalent among African Americans than white, European Americans. The goal of this study has been to elucidate environmental, hormonal, and cultural factors ...
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Antiproliferative Activity of a Dietary Supplement on Estrogen Receptor Positive and Negative Human Breast Adenocarcinoma Cell Lines
Torricelli Piera,
Antonelli Francesco,
Ferorelli Pasquale,
De Martino Angelo,
Shevchenko Anna,
Beninati Simone
Issue:
Volume 2, Issue 2, March 2014
Pages:
29-32
Received:
10 February 2014
Published:
30 March 2014
Abstract: A commercial food supplement called Citozym (CIZ), was tested for antiproliferative activity against estrogen receptor (ER)-positive MCF-7 and (ER)-negative BT-20 human breast cancer cells, performing two independent experiments using SRB assay. A CIZ concentration of 100mg/mL, showed the most potent antiproliferative activity for cells in a potential range for further investigation on estrogen-insensitive breast cancer therapy
Abstract: A commercial food supplement called Citozym (CIZ), was tested for antiproliferative activity against estrogen receptor (ER)-positive MCF-7 and (ER)-negative BT-20 human breast cancer cells, performing two independent experiments using SRB assay. A CIZ concentration of 100mg/mL, showed the most potent antiproliferative activity for cells in a potent...
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The Role of Using Ultra Short Pulsed Lasers in Determining Dynamical Dependent of Free Electron Density in the Skin Tissue for Treatment of Skin Cancer
S. Nasrin Hosseinimotlagh,
Samira Khazraei
Issue:
Volume 2, Issue 2, March 2014
Pages:
33-41
Received:
5 March 2014
Accepted:
10 April 2014
Published:
20 April 2014
Abstract: We study on the new advances in laser cell surgery for skin cancer treatment and investigate on the working mechanisms of femtosecondlaser. Also, influences of the critical electron density and radiation intensity on the free-electron density for ablation on the epidermis and dermis tissues are investigated. Our studies on this work, show that if the amount of radiation intensity of pulsed laser is increased then the distance of focal spot is decreased also the amount of time dependent free- electron density become more and more, such that this case is proper for skin cancer treatment. Also, our calculations for skin tissue show that optimum time dependent free electron density for dermis layer at angle 16˚ and 22˚ which is a function of wavelength, beam width, beam radius, amplitude of the beam radiation strength and pulse duration is more than for epidermis layer
Abstract: We study on the new advances in laser cell surgery for skin cancer treatment and investigate on the working mechanisms of femtosecondlaser. Also, influences of the critical electron density and radiation intensity on the free-electron density for ablation on the epidermis and dermis tissues are investigated. Our studies on this work, show that if t...
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